DNA–polymer conjugates for immune stimulation through Toll-like receptor 9 mediated pathways
نویسندگان
چکیده
منابع مشابه
Toll-Like Receptor Signaling Pathways
Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes. TLRs signal through the recruitment of specific adaptor molecules, leading to activation of the transcription factors NF-κB and IRFs, which dictate the outcome of innate immune responses. During the past decade, the precise mechanisms und...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2014
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2013.11.022